BioStellar™ Plate is an advanced microfluidic cell culture plate specifically designed for connection co-culturing categorized in multi-organ microphysiological systems (MPS). This innovative plate features an integrated kinetic pump mechanism that facilitates efficient fluid perfusion, eliminating the need for external pumps and tubing. This design significantly streamlines experimental setups, enhancing usability for researchers. Additionally, the BioStellar™ Plate offers versatile options for cell culture formats, which can be combined with commercially available cell culture inserts or Cell Desk. This flexibility allows users to tailor their experimental designs to meet specific research objectives. The incorporation of such features positions the BioStellar™ Plate as a valuable tool in the study of complex biological interactions and the development of more physiologically relevant in vitro models.