トップ画像

News from the S-BIO Business Division, Sumitomo Bakelite Co., Ltd.

SUMILON™ Companion Plate Opens a New Stage

in Automation of Cell Culture

画像1

S-BIO are pleased to introduce an application featuring the SUMILON™ Companion Plate (for Cell Culture Insert) — a solution designed to improve efficiency and reduce labor in cell culture workflows using cell culture insert.

In this application, Caco-2 cells (1.0 × 10⁵ cells/well) were cultured for 21 days by combining the Panasonic Production Engineering Co., Ltd. all-in-one automated cell culture system with the SUMILON™ Companion Plate. Because the SUMILON™ Companion Plate enables medium exchange without removing the insert, it demonstrates high compatibility with the robotic arm operations of automated culture systems, achieving a stable and streamlined automated workflow throughout the entire culture period.

Evaluation results confirmed that TEER values — an indicator of cell layer barrier function — showed a consistent increase over the culture period, confirming successful formation of intestinal barrier function. Furthermore, gene expression analysis of intestinal differentiation markers VIL1, CLDN7, and MDR1 revealed that expression levels were maintained at equivalent levels compared to the manual culture method (Conv.), demonstrating that normal intestinal epithelial cell function and phenotype are preserved even under automated culture conditions.

In addition, a membrane permeability assay using Lucifer Yellow yielded results equivalent to those obtained with manual culture, indicating that automation has no adverse effect on assay accuracy.

These results demonstrate that the SUMILON™ Companion Plate exhibits high compatibility with automated culture systems and is expected to serve as a versatile platform for automating and streamlining intestinal barrier function evaluation and drug permeability assays, with broad potential applications in drug discovery research and safety assessment.

Read More
What's new

Stay tuned for news about S-BIO

Exhibition at ACGG2026, an international symposium on glycoscience

画像2

S-BIO exhibited at the 15th Asian Community of Glycoscience and Glycotechnology (ACGG) Symposium, an international academic event in the field of glycoscience held at the National Institute of Advanced Industrial Science and Technology (AIST) in Tsukuba, Ibaraki, Japan from 3 to 6 October 2026. The ACGG symposium brings together glycoscience researchers from across Asia and Oceania. The event attracted many researchers and related professionals from Japan and overseas, providing a platform for active discussion and exchange. During the symposium, we showcased our research support tools and their applications at our exhibition booth and in a short presentation. Many visitors stopped by our stand, showing strong interest in our products, including our BlotGlyco™ glycan purification kit. There was particular interest in the ongoing use of BlotGlyco™ in the Japanese national glycoscience research initiative, the Human Glycome Atlas Project (iGCORE), leading to many specific questions and consultations. We also had the opportunity to extensively exchange ideas with researchers and companies from various countries, making the event a valuable occasion for future technical collaboration and international business development. S-BIO is committed to providing products and services that support glycoscience research and will continue to value feedback from the research community.

画像3

I’m Chieko Inoue from the S-BIO Business Division. Recently, I took part in a marathon event. While I had always been better at long-distance running than sprinting, it had been a full 20-plus years since I last ran seriously — and on top of that, the race was 10 kilometers. I was filled with anxiety, wondering, 'Can I really make it to the finish line?' Still, I started by buying a pair of running shoes, and about two months before the race, I began practicing with late-night runs around the outer perimeter of Osaka Castle. Once I actually got out there and started running, listening to my favorite music and going at my own pace, my anxiety quickly melted away — and before I knew it, running had become a genuinely enjoyable part of each day. When race day finally arrived, I crossed the 10-kilometer finish line with a smile, safe and sound! The sense of accomplishment from completing the run was immense, of course — but what surprised me even more was a different kind of change that came with developing a habit of running. In the course of everyday life, I began to notice, almost unexpectedly, a feeling of mental clarity and sustained concentration. Curious, I looked into it, and apparently the positive effects of aerobic exercise on brain function have been widely reported in recent years across the fields of neuroscience and exercise physiology. Aerobic exercise — running included — is even referred to in the worlds of medicine and brain science as a "natural antidepressant," and the following mechanisms are known to be involved:

Improved memory and learning efficiency (the hippocampus and BDNF)

Exercise is said to promote the expression of brain-derived neurotrophic factor (BDNF), which stimulates neurogenesis in the hippocampus — the region responsible for memory and learning. For those who regularly process vast amounts of information and literature, this could be a powerful ally in boosting the efficiency of information intake.

Clearer thinking and better judgment (activation of the prefrontal cortex)

Increased blood flow activates the prefrontal cortex, which governs logical thinking and decision-making. It may be no coincidence that you often hear people say, "A hypothesis or idea I'd been stuck on no matter how long I sat at my desk suddenly clicked while I was out running."

Stress relief and mental refreshment (serotonin and dopamine)

Moving the body at a steady rhythm promotes the release of neurotransmitters such as serotonin, which stabilizes mood, and dopamine, which enhances motivation — naturally resetting the mental fatigue that builds up from long hours of desk work.

In today's world, where so much of our time is spent in front of a screen, thinking and processing — running again after 20 years has reminded me that moving the body might just be the greatest cognitive booster of all. If you ever find yourself thinking, 'My mind is going in circles' or 'I need to give my brain a reset,' why not lace up your favorite sneakers and head outside for a light jog in the fresh air? You might just find that an unexpected flash of inspiration rises up from beneath your feet.

We also share information on social media.

X
LinkedIn

This email is sent to customers who exchanged business cards at exhibitions, participated in our campaigns, or made inquiries via our website etc. We use cookies, web beacons, and access logs on our website and in emails sent from us to analyze usage, conduct marketing and sales activities, and respond to inquiries.

Issued by: S-BIO Business Division, Sumitomo Bakelite Co., Ltd.

2-5-8 Higashi-Shinagawa, Shinagawa-ku, Tokyo, 140 0002, Japan
Inquiry about S-BIO: https://inquiry.sumibe.co.jp/m/e_s-BIO

Unsubscribe from this newsletter

https://www.sumibe.co.jp

Copyright2026 SUMITOMO BAKELITE CO., LTD. All Rights Reserved.