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News from the S-BIO Business Division, Sumitomo Bakelite Co., Ltd.
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| Introduction of Research Paper using BlotGlyco™ |
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Glycans play important roles in diverse cellular functions and serve as disease biomarkers; however, conventional methods have faced challenges in accurately analyzing complex N-glycans. Here, we introduce a paper published in PLOS ONE titled “Optimizing the preparation of labeled N-glycans for rapid, simplified, and high-precision analysis.”
This study proposes a rapid and highly precise N-glycan analysis method using the original “BlotGlyco™” technology. A key feature is the remarkable improvement in separation and detection accuracy achieved by specific labeling with an S-phosphorylation analog. This enabled precise analysis of glycans derived from human serum, urine, and CHO cell membranes, achieving consistently high-precision and highly reproducible data.
It overcomes previous challenges in identifying and comparatively analyzing complex glycans, establishing an effective technological platform for glycan biomarker discovery, disease research, and clinical diagnostic development. This study is expected to contribute to the advancement of disease diagnostics and life science research as a new standard method for glycan analysis.
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Please click "Read More" for more information. |
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